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Hsp60 is involved in protein folding and hsp70 has a role in regulating the heat shock response as well as membrane translocation. While hsp60 is found in the mitochondria, hsp70 is found in the eukaryotic cytosol, ER and mitochondria. Both families of proteins actually function for protein translocation and transport as well as folding and assembly (“Molecular Chaperones”). In aging and diseased tissues, high amounts of hsp60 are found in people with atherosclerosis, acute coronary syndromes and angina, while hsp70 is found in those with peripheral as well as renal vascular diseases (Frostegard & Pockley 201-202).