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The research found out that Benzodiazepine is more effective in managing stress than placebo. BZ reduces the disabling effects of anxiety quickly. BZs catalyze the action of GABA, a form of natural anxiety relief. As a result, a person becomes calmer. Research also indicates that BZs reduce the activity of Serotonin which causes anxiety in the body. Hildago et al (2001) used a Meta-analysis approach to study the effectiveness of BZs in the reduction of anxiety, and they found out that BZs reduced stress more than any other anti-depressant.